IMR Press / EJGO / Volume 25 / Issue 4 / pii/2004216

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Postoperative patient-controlled analgesia with intravenous tramadol, intravenous fentanyl, epidural tramadol and epidural ropivacaine+fentanyl combination

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1 Department of Anaesthesiology and Reanimation, Faculty of Medicine, University of Gaziantep, Gaziantep (Turkey)
2 Department of Obstetrics and Gynaecology, Gaziantep (Turkey)
Eur. J. Gynaecol. Oncol. 2004, 25(4), 498–501;
Published: 10 August 2004

Purpose: The aim of this study was to compare the effects of IV tramadol, IV fentanyl, epidural tramadol, and an epidural ropi­vacaine+fentanyl combination in patient-controlled analgesia (PCA) after lower abdominal surgery. Methods: Eighty adult patients undergoing lower abdominal surgery were randomly allocated to one of four groups to receive analgesics with PCA pumps. Patients in group I received IV tramadol, group II patients IV fentanyl, group III patients epidural tra­madol, and group IV patients an epidural infusion of 0.125% ropivacaine + 2 µg ml-1 fentanyl combination. Analgesic effectiveness and side-effects were assessed at 1, 2, 3, 4, 5, 6, 8, 12, 16, 20, and 24 hours after surgery. Results: Adequate analgesia was achieved in all groups. The analgesia was highest in group IV (p < 0.05), and lowest in group III patients (p < 0.05). Eleven patients (55%) in group I and eight patients (40%) in group II suffered from nausea/vomiting. Conclusion: Although adequate pain relief was achieved with all regimens that were used in the study, intravenous tramadol and intravenous fentanyl are associated with high a incidence of nausea and vomiting.

Postoperative analgesia
Patient-controlled analgesia
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