IMR Press / EJGO / Volume 25 / Issue 2 / pii/2004159

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Angiomyofibroblastoma of the vulva: report of a case

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1 Deparrment of Obstetrics and Gynaecology, “Piemonte Orientale” University, Novara (Italy)
Eur. J. Gynaecol. Oncol. 2004, 25(2), 253–254;
Published: 10 April 2004

A case of solitary angiomyofibroblastoma of the vulva in a l 6-year-old woman was examined by histology and immunohistochem­istry. Microscopic examination of the tumor revealed typical features of a mesenchymal neoplasm, composed of bundle spindle cells with low cellular density, rich in collagen fibers and 'thin-walled blood vessels. Immunohistochemistry revealed immunoreactivity for progesterone receptor, CD34, desmin and vimentin, tumor cells expressing positivity, but not for estrogen receptors. The stains for the muscle-specific actin and S-100 were negative. These results were mostly consistent with those of previous reports and suggest that the tumors cells were derived from primitive mesenchymal cells which occur normally in this region and show the potential for diverse lines of myoid differentiation.

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