IMR Press / EJGO / Volume 25 / Issue 1 / pii/2004123

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Large cell neuroendocrine carcinoma of the uterine corpus metastatic to brain and lung: Case report and review of the literature

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1 Department of Pathology, Ege University Faculty of Medicine, Ivnir (Turkey)
2 Department of Obstetrics and Gynecology, Ege University Faculty of Medicine, Ivnir (Turkey)
Eur. J. Gynaecol. Oncol. 2004, 25(1), 109–112;
Published: 10 February 2004

Neuroendocrine carcinoma of the uterine corpus is a rare aggressive tumor with a similar unfavorable outcome to that of the cervix. The large cell type is considerably rarer than the small cell neuroendocrine carcinoma of the uterine corpus. We report a case of a 52-year-old woman who presented with a large cell neuroendocrine tumor of the uterine corpus with very aggressive clinical behavior, cerebral and pulmonary metastases six and four months after initial diagnosis and adjuvant radiotherapy, respectively. Despite successful surgical extirpation of the cerebral metastatic lesion she did not respond to chemotherapy and died four months after disease recurrence.

Large cell neuroendocrine carcinoma
Uterine corpus
Cerebral metastasis
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