IMR Press / EJGO / Volume 23 / Issue 3 / pii/2002150

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Identification of high risk patients with endometrial carcinoma. Prognostic assessment of endometrial cancer.

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1 Department of Obstetrics and Gynecology, H. San Raffaele, University of Milan, Milan (Italy)
2 Department of Pathology, H. San Raffaele, University of Milan, Milan (Italy)
3 Department of Statistics, H. San Raffaele, University of Milan, Milan (Italy)
Eur. J. Gynaecol. Oncol. 2002, 23(3), 216–220;
Published: 10 June 2002

Objectives: To verify the importance of DNA ploidy on clinical outcome in endometrial carcinoma and to investigate whether the prognostic information obtained by this variable is independent from other clinical-pathologic features. Materials and methods: Univariate and multivariate analysis of clinical and pathologic prognostic factors obtained from 203 con­secutive cases of endometrial cancer, that had been surgically treated in our hospital, were performed. Results: Significant prognostic factors according to the Kaplan-Meier method were age at the time of diagnosis, grade of diffe­rentiation, peritoneal cytology, node involvement, vascular invasion, myometrial infiltration and ploidy. At multivariate analysis only DNA ploidy resulted to be an independent variable. Conclusions: In our analysis DNA content is the only parameter which preserved prognostic significance in multivariate analysis.

Endometrial cancer
Prognostic factors
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