IMR Press / EJGO / Volume 22 / Issue 5 / pii/2001188

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Ovarian capillary hemangioma and stromal luteinization: a case study with hormonal receptor evaluation

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1 Department of Pathology, Medical Faculty, Aristotelian University, Thessaloniki, Greece
2 Division of Surgery, General Clinic of Thessaloniki, Medical Faculty, Aristotelian University, Thessaloniki, Greece
3 Laboratory of Histology and Embryology, Medical Faculty, Aristotelian University, Thessaloniki, Greece
Eur. J. Gynaecol. Oncol. 2001, 22(5), 369–371;
Published: 10 October 2001

Background: Ovarian hemangiomas are rare tumors, most of them asymptomatic, and of the cavernous type. Six of the reported cases were accompanied by stromal luteinization. There is a debate whether these luteinized cells promote the growth of the vascu­lar lesion or just represent a stromal reaction. Case: A 71-year-old female was incidentally found to have a small capillary hemangioma in her left ovary, surrounded by a rim of luteinized stromal cells. Immunohistochemical investigation revealed the presence of estrogen and progesterone receptors in the endothelial cells of the lesion. Conclusion: Our histological and immunohistochemical findings, as well as data from the literature, support the view that at least some vascular lesions may result from hormonal stimulation.

Ovarian hemangioma
Stromal luteinization
Estrogen receptors
Progesterone receptors
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