IMR Press / EJGO / Volume 21 / Issue 3 / pii/2000165

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Prognostic value of bcl-2, p53 and Ki-67 in invasive squamous carcinoma of the uterine cervix

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1 Gynecology Institute, Padua University, Italy
2 Pathology Institute, Padua University, Italy
3 Statistician, Padua University, Italy
Eur. J. Gynaecol. Oncol. 2000, 21(3), 267–272;
Published: 10 June 2000
Abstract

The aim of this study was to evaluate the immunohistochemical expression of the markers bcl-2, p53 and Ki67 and their relation to the classical clinical-pathological prognostic factors in invasive squamous cellular carcinoma of the cervix. Since bcl-2 and p53 are implicated in the regulation of programmed cell death, very probably they play a role in carcinogenesis and consequently become prognostic factors.

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