IMR Press / EJGO / Volume 2 / Issue 1 / pii/1981003

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

A planned prospective study of combined treatment in stage Ⅲ epithelial ovarian cancer

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1 Gynecol. and Obstet. Clinic, University of Padua (Italy)
2 Department of Medical Oncology, Padua General Hospital (Italy)
Eur. J. Gynaecol. Oncol. 1981, 2(1), 17–21;
Published: 10 February 1981

In a planned prospective study 39 consecutive patients with stage III ovarian cancer have been admitted in two years. All patients have received initial extensive surgery followed on as out patients basis by 5 courses of A-Cy chemotherapy and by a second operation and further non cross resistant chemotherapy with Platinum, Hexamethyl-Melamine, Polymelphalan; 24 have been found pathologically free of disease at second surgery, and 34/39 are clinically free of disease while reporting. These data, exactly collected and evaluated are consistent with our (previously reported) empyrical observation that adjuvant surgery interspersed with courses of aggressive chemotherapy may render free of disease the majority of patients, prolong survival, and possibly cure a portion of this population. 

Ovarian carcinoma
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