IMR Press / EJGO / Volume 19 / Issue 5 / pii/1998202

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Is there an effect of perioperative blood transflusion on the outcome of radical hysterectomy with lymphadenectomy for cervical cancer in South Africa?

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1 Department of Obstertrics and Gynecology, University Hospital Leiden, Leiden, Netherlands
2 Department of Obstetrics and Gynecology, Groote Schuur Hospital, Cape Town, South Africa
3 Department of Statistics and Epidemiology, University Hospital Leiden, Leiden, Netherlands
Eur. J. Gynaecol. Oncol. 1998, 19(5), 458–463;
Published: 10 October 1998
Abstract

The aim of this study was to investigate whether there is an effect of perioperative blood transfusion on the outcome of radical hysterectomy with lymphadenectomy for cervical cancer. One hundred and thirty-one patients with cervical cancer were treated by Wertheim radical hysterectomy in the period from 1984- 1991. Eighty-six patients received blood transfusions during surgery or within two weeks, whereas 45 patients did not receive any blood transfusion. Transfused and non-transfused patients did not differ with respect to mean age, race, weight, FIGO-stage, cell-type, grade, size, depth of invasion and nodal involvement. Transfused patients had more blood loss, longer surgical time and lower haemoglobin levels. Using log rank analysis, the calcu­lated five-year survival was 81 % for the transfused group and 84% for the non-transfused group, a non-significant difference. The five-year disease-free survival rate was 87% for the transfused group and 88% for the non-transfused group. This study suggests that perioperative blood transfusion does not adversely influence survival after the Wertheim operation for cervical cancer.

Keywords
Hysterectomy
Blood transfusion
Cervical cancer
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