IMR Press / EJGO / Volume 19 / Issue 2 / pii/1998136

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Angiogenesis as a prognostic factor in cervical carcinoma

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1 1st Department of Obstetrics & Gynecology, University of Catania, Catania, Italy
2 Department of Pathological Anatomy, P.O. S. Bambino, A.U.S.L. 3, Catania, Italy
Eur. J. Gynaecol. Oncol. 1998, 19(2), 158–162;
Published: 10 April 1998
Abstract

Angiogenesis and other prognostic factors have been studied among 32 recurrences and 28 deaths of 420 patients with cervical carcinoma operated in the 1 st Department of Obstetrics & Gynecology of Catania University. Prognostic factors were studied in comparison with a group of patients still alive and NED was followed for more than 60 months independently of stage and node involvement. Angiogenesis, nuclear grading 3, and lymphovascular invasion were factors common to all patients with negative prognosis. It seems that in the presence of these negative prognostic factors, we should adopt a more aggressive attitude in both our surgical strategies and adjuvant therapies, particularly preferring chemotherapy where angiogenesis is more significant.

Keywords
Angiogenesis
Cervical carcinoma
Prognostic factors
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