IMR Press / EJGO / Volume 18 / Issue 1 / pii/1997108

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Cytology, histology, and colposcopy in the diagnosis of neoplastic non-invasive epithelial lesions of the cervix

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1 Division of Human Pathology and Histology, Universita Cattolica del S. Cuore, Rome, Italy
2 Gynaecological and Obstetrical Institute, Universita Cattolica del S. Cuore, Rome, Italy
3 Internal Medicine Institute, Università Cattolica del S. Cuore, Rome, Italy
Eur. J. Gynaecol. Oncol. 1997, 18(1), 36–38;
Published: 10 February 1997

The purpose of our study was to examine the concordance among colposcopy, cytology, and histology in the diagnoses of intrae­ptthelial lesions of the uterine cervix. We compared the results of Pap tests, biopsies, and colposcopy in 190 patients, who had histo­logically proven CIN and/or HPV infection, using histology as “the gold standard”. The X'(chi square) test was used for the stati­stics analysis. The sensitivity of cytology for the detection of CIN was 70%, and was lower for LGL (low grade lesions) than for HGL (high grade lesions): 61.2% versus 88.5%, respectively (p<0.0001). We obtained a high rate of false negative smears (30%), with a relatively high rate of inadequate samples (59.6%). The sensitivity of colposcopy was 92%. Our results suggest that the Pap test alone is no longer sufficient for the screening of precancerous lesions of the cervix, and colposcopy is compulsory each time the smear is inadequate or altered.

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