IMR Press / EJGO / Volume 18 / Issue 1 / pii/1997106

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Breast preservation versus mastectomy Recurrence and survival rates of primary breast cancer patients treated at the UFK Bonn

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1 Department of Obstetrics and Gynaecology of the University of Bonn, Bonn, Germany
2 Institute for Medical Statistics of the University of Bonn, Bonn, Germany
3 Department of Radiology of the University of Bonn, Bonn, Germany
Eur. J. Gynaecol. Oncol. 1997, 18(1), 29–33;
Published: 10 February 1997
Abstract

The aim of this retrospective long-term analysis was to evaluate the approach of breast conservation in the light of the results obtained, on the basis of mastectomy, in patients with early breast carcinoma. Additionally, the effect of internal mammary and supraclavicular radiotherapy was analyzed. Therefore, local-regional recurrence (LRR) and survival rates were examined in 411 patients with Tl and T2 stages who had undergone either breast-preserving surgery with radiation or mastectomy. Individual risk factors such as nodal status, lymphangiosis carcinomatosa and age of the patients were evaluated, too. The rate of local-regional recurrence in patients who were treated by mastectomy and conservative surgery was 9.2% and 11.0%, respectively, with relapse happening earlier in the latter group (median of 16 vs. 24 months). Survival rates, however, were not different in the two groups Tumour stage and nodal status had no influence on the local-regional recurrence rate in either group. In connection with lymphan­giosis carcinomatosa, however, the rate increased to 14.5% (mastectomy) and 19.0% (breast-preserving surgery), respectively. Patients ≤40 years had an even higher risk of LRR, with 20.6% when they underwent mastectomy and 30.8% following breast con­servation. Internal mammary and supraclavicular radiotherapy had no positive effect on the survival rates, neither in the mastec­tomy nor in the breast conservation group. As a conclusion, in more than 60% of all Tl stages, and more than 50% of all T2 stages, the therapeutic concept of breast preservation seems to be justified.

Keywords
Early breast cancer
Breast conservation
Radiation
Local-regional recurrence
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