IMR Press / EJGO / Volume 18 / Issue 1 / pii/1997105

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Does persistent postmenopausal bleeding justify hysterectomy?

Show Less
1 Division of Gynaecologic Oncology, Department of Obstetrics and Gynaecology, University of Ottawa, Ottawa General Hospital, Canada
2 Department of Obstetrics and Gynaecology, University of Manitoba, Women's Hospital, Winnipeg, Canada
Eur. J. Gynaecol. Oncol. 1997, 18(1), 26–28;
Published: 10 February 1997

Postmenopausal vaginal bleeding is an early sign of endometrial cancer. Persistent postmenopausal bleeding refers to uterine blee­ding for which no malignant cause can be demonstrated by endometrial sampling. Hysterectomy has routinely been performed in this group of patients because of a perceived risk of endometrial cancer. The objective of this study was to quantify the risk of endo­metrial cancer in patients undergoing hysterectomy for postmenopausal bleeding after benign histology on endometrial sampling. One thousand four hundred and sixty-three patients underwent a hysterectomy during the study period. Forty hysterectomies (2.7%) were performed for persistent postmenopausal bleeding. The final pathology of the 40 hysterectomy specimens demonstra­ted hyperplasia with atypia in four patients (10%), hyperplasia without atypia in 14 (35%), and other non malignant pathology in 22 (55%). There were no cases of carcinoma of the endometrium. We conclude that persistent postmenopausal bleeding with non malignant pathology on endometrial sampling is not an indication for hysterectomy.

Postmenopausal vaginal bleeding
Back to top