IMR Press / CEOG / Volume 48 / Issue 2 / DOI: 10.31083/j.ceog.2021.02.2293
Open Access Systematic Review
Clinical efficacy of aortic balloon occlusion during caesarean section in patients with placenta accreta spectrum disorders: a systematic review and meta-analysis
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1 Department of Obstetrics and Gynecology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, No.32 West Second Section First Ring Road, 610041 Chengdu, Sichuan, China
Clin. Exp. Obstet. Gynecol. 2021, 48(2), 234–244;
Submitted: 13 September 2020 | Revised: 7 November 2020 | Accepted: 13 November 2020 | Published: 15 April 2021
Copyright: © 2021 The Authors. Published by IMR Press.
This is an open access article under the CC BY 4.0 license (

Object: This systematic review and meta-analysis aim to examine evidence on the effectiveness and safety of aortic balloon occlusion (ABO) during caesarean deliveries in placenta accreta spectrum (PAS) disorders. Methods: MEDLINE, Science Citation Index, Elsevier,, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched for articles dated from database inception to February 2020. The primary outcomes were intraoperative blood loss volume (BLV) and hysterectomy rate. Results: Of the 793 articles, 11 were included in this study, with a total of 915 patients. Of the 535 patients who underwent ABO, 48 (9%) had placenta creta; 309 (57%), placenta increta; and 124 (23%), placenta percreta. Meta-analysis showed that ABO significantly reduced BLV and blood transfused volume (P < 0.001), and reduced the rate of hysterectomy (P< 0.001). The overall catheter-related complication rate was 3.36%. The primary outcomes were available for 60 patients with placenta percreta. Meta-analysis of these patients showed ABO was associated with a decrease in BLV (P < 0.001), but not a statistically significant reduction in hysterectomy (P = 0.48). Conclusions: ABO is effective at controlling haemorrhage and reducing the need for hysterectomy in PAS disorders, but it did not appear to be effective for uterine preservation in patients with placenta percreta.

Balloon occlusion
Placenta accreta
Placenta percreta
Caesarean section
2018SZ0230/Key projects of Sichuan Science and Technology Department
Fig. 1.
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