Objective: To investigate associations of the time
interval between hCG administration and oocyte pick up with oocyte maturation,
embryonic morphology, morphokinetics, and IVF outcome, in different age groups.
Design: A retrospective cohort study. Setting: An academic
medical center. Patients: Women who underwent IVF and ICSI cycles in
which all oocytes were incubated in a time lapse microscopy system (EmbryoScope).
Cycles were stratified by age and time from hCG exposure.
Interventions: None. Main Outcome Measures: Of 2185 IVF/ICSI
OPU cycles, 820 cycles were included in the analysis. Final analysis was made on
796 cycles (4930 oocytes). Oocyte number and their maturity, fertilization rates,
and embryo quality defined by morphology and morphokinetics,
clinical pregnancy, and live birth rates. Results: The
median hCG-oocyte pick up (OPU) interval was 34.45 hours. Among women over age 36
years, longer intervals were associated with both a higher fraction of mature
oocytes (P
Announcements
Open Access
Original Research
Time interval between hCG administration and oocyte pick up: analysis of oocyte maturation, embryonic morphology, morphokinetics, and IVF outcome
Sivan Skvirsky1,*, Idit Blais1, Shirly Lahav-Baratz1, Mara Koifman1, Zofnat Wiener-Megnazi1, Martha Dirnfeld1
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1
Department of Obstetrics and Gynecology, Division Reproductive Endocrinology-IVF Carmel Medical Center, Bruce and Ruth Rappaport Faculty of Medicine, 3100000 Haifa, Israel
*Correspondence: sivanbi@yahoo.com (Sivan Skvirsky)
Clin. Exp. Obstet. Gynecol. 2021, 48(2), 402–409;
https://doi.org/10.31083/j.ceog.2021.02.2284
Submitted: 5 September 2020 | Revised: 1 December 2020 | Accepted: 4 December 2020 | Published: 15 April 2021
Copyright: © 2021 The Authors. Published by IMR Press.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract
Keywords
Oocyte pick up
hCG interval
Mature oocytes
Embryo morphology
Morphokinetics
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Fig. 1.