IMR Press / CEOG / Volume 47 / Issue 4 / DOI: 10.31083/j.ceog.2020.04.5311
Open Access Case Report
Outcome of shared decision-making in a patient with primary herpes gingivostomatitis during pregnancy: a case report
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1 Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
2 Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
3 Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei, Taiwan
4 Division of Infertility, Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan
5 Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
*Correspondence: (YUNG-LIANG LIU)
Clin. Exp. Obstet. Gynecol. 2020, 47(4), 604–606;
Submitted: 20 June 2019 | Accepted: 24 September 2019 | Published: 15 August 2020
Copyright: © 2020 Huang et al. Published by IMR press.
This is an open access article under the CC BY 4.0 license

Purpose: The authors present the case of a woman in the 20th week of pregnancy with herpes simplex virus (HSV)-related gingivostomatitis. They also provide information regarding the benefits and risks of acyclovir, valacyclovir, famciclovir, and shared decision-making (SDM) through which valacyclovir was selected. Case Report: A 26-year-old primigravida woman who denied having a history of systemic diseases presented with fever, general malaise, and abdominal pain at 20 weeks of gestation. As no strong evidence supports any current treatment for primary maternal HSV-1 gingivostomatitis during pregnancy, the authors used three key steps of SDM, namely choice talk, option talk, and decision talk, to help the patient make a decision based on the benefits and ill-effects of treatment with acyclovir, valacyclovir, and famciclovir. Valacyclovir was administered for one week. Her general condition improved gradually, and the symptoms abated without recurrence of fever. Conclusions: Thus, SDM-based treatment was effective in this patient.

Antiviral therapy
Herpes gingivostomatitis
Shared decision-making
MOST 106-2314-B-016-004/Ministry of Science and Technology, Taiwan, ROC
MOST 107-2314-B-016-065-MY2/Ministry of Science and Technology, Taiwan, ROC
TSGH-C106-081/ Tri-Service General Hospital
TSGH-C107-082/Tri-Service General Hospital
TSGH-C108-116/Tri-Service General Hospital
TSGH-PH-105-4/Tri-Service General Hospital, Penghu Branch
Figure. 1
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