Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Purpose: To evaluate the effect of clinical and demographic factors on the further course of pregnancy and post-procedure complications in healthy and high-risk pregnancies. Materials and Methods: Data of 230 amniocenteses with normal (n=174) and abnormal genetic findings (n=56) were collected retrospectively. Details of birth, neonatal condition, patient characteristics, and post-procedure complications were analysed. Results: The mean maternal age at amniocentesis was 34.50 ± 5 years-old. One hundred (43.48%) were followed by at least one complication. Fetal death occurred after 11 (4.78%) procedures including seven with genetic disorders. There was no significant difference in complication rates between study groups, except for fetal death, which was significantly more common in high-risk pregnancies (p = 0.0017). Abdominal pain correlated with pyrexia and vaginal bleeding. Conclusion: The most severe complications were associated with fetal genetic disorders. The authors conclude that amniocentesis is a safe procedure; however, significant correlations between the incidence of certain complications may be relevant in planning antenatal care.