IMR Press / CEOG / Volume 46 / Issue 3 / DOI: 10.12891/ceog4663.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Bilateral pulmonary agenesis diagnosed in the 13 th week of gestation - a case report and literature review
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1 Ultramedica Clinic, American Medical Academy, Belgrade, Serbia
2 National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan
3 Department of Medicine, Nazarbayev University, School of Medicine, Astana, Kazakhstan
4 Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
5 Department of Cellular Pathology, PathLinks Pathology Services, Lincoln County Hospital, Lincoln, Uniyed Kingdom
*Correspondence: (M. TERZIC)
Clin. Exp. Obstet. Gynecol. 2019, 46(3), 479–481;
Published: 10 June 2019

Bilateral pulmonary agenesis (BPA) is a rare congenital lung malformation incompatible with extra-uterine life, diagnosed by various prenatal imaging modalities in the second and third trimesters. Essentials for diagnosis are complete absence of lungs and bronchi and no pulmonary vascular supply. In the present case, both convex and vaginal ultrasound scan performed at 13th GW revealed an anechoic content in the entire fetal thorax with no evidence of pericardial effusion, fetal heart diseases, or any other accompanying congenital malformations. On three-vessel view (3VV), bifurcation of pulmonary artery could not be identified, which confirmed the diagnosis of BPA. In conclusion, clinical importance of combining the up-to-date technological tools and clinical expertise in establishing the diagnosis as early as in the first trimester allows the clinicians to terminate the pregnancy with the lowest incidence rate of eventual complications related to the procedure. According to the literature data, this is the first and therefore unique case of BPA diagnosed in the 13th week of gestation.

Bilateral pulmonary agenesis
Bilateral lung agenesis
Lung aplasia
Ultrasound scan
First trimester
Figure 1.
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