IMR Press / CEOG / Volume 44 / Issue 2 / DOI: 10.12891/ceog3385.2017

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Virtopsy in conjoined ischiopagus twins
Show Less
1 Unit of Obstetrics and Gynecology, IRCCS A.O.U. San Martino IST, Genoa, Italy
2 Department of Pathology, University of Genoa and IRCCS A.O.U. San Martino IST, Genoa, Italy
3 Department of Radiology, IRCCS A.O.U. San Martino IST, Genoa, Italy
4 Department of Pathology, University of Genoa and IRCCS G. Gaslini Institute, Genoa, Italy
Clin. Exp. Obstet. Gynecol. 2017, 44(2), 288–291;
Published: 10 April 2017

Purpose of investigation: To propose a multidisciplinary protocol for postmortem disclosure of complex fetal malformations, comparing ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and autopsy in a case of conjoined ischiopagus twins. Materials and Methods: A screening second-trimester ultrasound diagnosed ischiopagus twins at 20 gestational weeks in a 31- year-old woman without any previous ultrasound examination. The couple decided for pregnancy termination. The formalin-fixed fetuses underwent full-body CT, MRI, and autopsy. Results: ultrasound accurately diagnosed ischiopagus twins. CT was very accurate in the description of bone components. MRI allowed better visualization of the visceral organs than CT. Only autopsy could disclose the aspect of the two gastrointestinal tracts and the external genitalia. Conclusions: Prenatal ultrasound represents the standard diagnostic exam for conjoined twins. CT-MRI virtual autopsy (virtopsy) may be an option if the couple refuses to authorize necropsy or may be useful to plan a minimally invasive autopsy preserving the external phenotype.
Computed tomography
Conjoined twins
Magnetic resonance imaging
Back to top