IMR Press / CEOG / Volume 20 / Issue 3 / pii/1993024

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

The effect of pethidine hydrochloride on the cervical muscles in the active phase of labour

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1 University Department of Obstetrics and Gynecology, Ljubljana, Slovenia
Clin. Exp. Obstet. Gynecol. 1993, 20(3), 145–150;
Published: 10 September 1993

The effect of pethidine hydrochloride (PHC) on the smooth muscles of cervix was studied in the active phase of induced labour in 27 primiparous women. The Electromyographic (EMG) root mean square (RMS) which provides information about the amplitude (intensity) of muscular cervical activity, and the median frequency (MF) which represents the EMG frequency spectrum were analyzed in connection with the intensity of intra-uterine pressure (IIUP). The RMS significantly decreases after the application of PHC, while the IIUP significantly increases. The effect of the applied drug disappears in one hour's time. The MF values increase insignificantly after the application and change in the opposite direction to the change of MSR. The change RMS, MF and IIUP values do not correlate with the duration of the active phase of labour.

Smooth cervical muscles
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