Dear Colleagues,
Cardiovascular diseases including atherosclerosis, myocardial infarction, heart failure, and their complications contribute significantly to the burden of morbidity and mortality for all people. Even though massive advances have been made in treating cardiovascular diseases, more sensitive protein and other biomarker assays have been clinically used to detect myocardial injury, although we remain far from realizing improvements in cardiovascular diseases risk assessment. Globally, cardiovascular diseases remain the leading cause of disease burden. Therefore, accurate early diagnosis of cardiovascular diseases has important clinical significance. There is an urgent need to develop new diagnostic markers for cardiovascular diseases.
Over the past decade, extensive optimization of protein biomarkers such as CK-MB, cTn, cMyBP-C, NT-proBNP, and C-reactive protein have led to the development of high-sensitivity assays, which have proven to be extremely beneficial in clinical practice. A novel approach in the combining complementary biomarkers is highly attractive. Recently, ncRNA species, including miRNA, lncRNAs and circRNAs, have emerged as biomarkers of cardiac injury that can complement protein biomarkers with greater specificity. The development of new biomarkers of cardiovascular disease can facilitate the understanding of the molecular mechanisms by which cardiovascular disease occurs, predict the disease risk, determine the disease trajectory along with the prognosis, and provide guidance in the formulation of personalized treatments.
In this Special Issue, we will focus on current research advances in molecular diagnosis and novel biomarkers of cardiovascular diseases. The goal of this Special Issue is to provide the most updated and comprehensive discoveries and opinions to discuss biological characteristics of potential biomarkers as well as emphasize their clinical significance, which may provide the foundation for future applications in cardiovascular disease diagnosis.
Prof. Lihua Sun
Guest Editor
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.
- Open Access Original ResearchAssociation between the C-Reactive Protein–Albumin–Lymphocyte (CALLY) Index and Adverse Clinical Outcomes in CAD Patients after PCI: Findings of a Real-World StudyYing Pan, Ting-Ting Wu, Chang-Jiang Deng, Zhi-Hui Jiang, ... Xiang XieRev. Cardiovasc. Med. 2024, 25(4), 111; https://doi.org/10.31083/j.rcm2504111(This article belongs to the Special Issue Novel Biomarkers of Cardiovascular Disease and their Applications in Clinical Practice)13Downloads77Views
- Open Access Original ResearchCystatin C to Left Ventricular Ejection Fraction Ratio as a Novel Predictor of Adverse Outcomes in Patients with Coronary Artery Disease: A Prospective Cohort StudyYi Ning, Kai-Yang Wang, Xuan Min, Xian-Geng Hou, ... Xiang XieRev. Cardiovasc. Med. 2023, 24(9), 260; https://doi.org/10.31083/j.rcm2409260(This article belongs to the Special Issue Novel Biomarkers of Cardiovascular Disease and their Applications in Clinical Practice)93Downloads157Views