- Cardiovascular Department, Harbin Medical University, Harbin, Heilongjiang, ChinaInterests: coronary artery disease; gut microbiome; lipids; acute coronary syndrome; atherosclerosis; imaging; angina pectoris stents; optical coherence tomographySpecial Issues and Topics in IMR Press journalsSpecial Issue in Multimodality Imaging in Acute Coronary Syndrome
Gut microbiome has been implicated in the progression of cardiovascular diseases (CVD). The composition of gut microbiome is altered in atherosclerosis, hypertension, arrhythmia, and heart failure. Emerging studies have identified that the gut microbiomes can regulate host nutrition and energy metabolism, maintain the integrity of intestinal mucosal barrier, regulate immunity, and suppress pathogens. Thus, the effects of imbalances in microbe–host interactions on homeostasis should not be underestimated. In addition, it has been recognized that the metabolites of the gut microbe play a critical role in health and disease. Various substances from dietary sources are metabolized into small molecules in the gut through gut microbes, mainly including trimethylamine-N-oxide (TMAO), short chain fatty acids (SCFAs), uremic toxins, and bile acids. They have the potential to serve as new biomarkers for the diagnosis, treatment, and prognostic assessment of CVD.
The purpose of this special issue is to focus on the interaction between gut microbes and CVD from multiple perspectives of molecular mechanisms to clinical applications. We are soliciting original papers and meaningful reviews from experts to present the current status and future prospects of gut microbiome in CVD. The topics of interest include but not limited to:
• Gut microbiome in the pathogenesis of CVD
• Analysis of the fecal metagenome and metabolome in CVD
• Microbiota in development and management of CVD
• Clinical application of gut microbes and metabolites in CVD
• New discovery of metabolites of gut microbes related to CVD
• Diet, gut microbes and CVD
Prof. Jinwei Tian
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.