The Management of Long QT Syndromes

Dear Colleagues,

Congenital deaf-mutism with prolongation of the QT interval and sudden death was first described in 1957. Independent descriptions of heritable QT prolongation without congenital hearing loss were independently reported in 1963 and 1964. In 1964, quinidine syncope was said to result from paroxysmal and repetitive ventricular fibrillation. These arrhythmias were first described as Torsades de Pointes in 1966.

Since these initial descriptions about 60 years ago, significant progress has been made in our understanding of both congenital and acquired long QT syndromes as well as the potentially deadly arrhythmia Torsades de Pointes. In this special issue of Reviews in Cardiovascular Medicine dedicated to the management of long-QT interval syndromes, we hope to address these topics in detail. We will explore current management strategies and goals that are, as yet, unattained. We seek submission of reviews and original research pertaining to topics such as congenital LQTS, acquired LQTS, ion channels and repolarization reserve, pharmacotherapy, sympathectomy, pacemakers and implantable cardioverter defibrillators. Original opinion pieces addressing areas of controversy in LQTS will be welcome. Additionally, authors with suggestions about ways to approach gaps in our knowledge of these entities and their treatment are encouraged to submit their thoughts and hypotheses about promising pathways.

Prof. Richard G. Trohman
Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.