Pathophysiology, Diagnosis, Treatment, and Prognosis of TakoTsubo Syndrome (TTS) What is Known and What is to be Known – Volume 2

Dear Colleagues,

TakoTsubo Syndrome (TTS) is an acute cardiac condition that poses important differential diagnostic questions with other acute conditions such as acute coronary syndrome or acute heart failure. Though its classical form is known for the typical pattern of left ventricular apical ballooning related to stressful conditions, diverse atypical presentations can be observed both in terms of wall motion abnormalities and precipitating triggers and, importantly, epidemiological data confirm that it does not affect only postmenopausal women. Complete recovery of systolic function is expected, as imaging techniques demonstrate absence of irreversible myocardial damage. However, observational studies carried out over the last 20 years have underscored unexpected prognostic implications of the disease. Patients with TTS exhibit a substantial risk of adverse events and even mortality and should be considered a vulnerable population. Pathophysiology of TTS remains largely elusive and to deeply understand mechanisms of the disease is essential to pave the way to specific treatments aimed at improving prognosis and, especially, prevent recurrences.

The present Special Issue is aimed at presenting what is known, what is the most recent evidence and what remains to be understood in the field of TTS. Therefore, submission of original research papers and review articles dealing with the pathophysiology, diagnosis, treatment, and prognosis of TTS is eagerly welcome.

Assoc. Prof. Giuseppe Andò

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.