Dear Colleagues,
For patients with end-stage kidney disease (ESKD) undergoing dialysis, both hemodialysis (HD) and peritoneal dialysis (PD), the clustering of traditional and non-traditional risk factors drives an excess rate of coronary artery disease (CAD). The incidence, severity and mortality of CAD, as well as the number of complications of therapy, are higher in dialysis patients than in non-ESKD disease population.
ESKD patients with CAD are more likely to be asymptomatic compared with those with CAD and preserved kidney function. This can hinder the correct identification of CAD and the appropriate risk stratification and management, potentially resulting in worse outcomes. Moreover, hemodialysis (HD) treatment may also promote or worsen myocardial damage while promoting arrhythmias due to rapid changes in electrolyte balance. Moreover, in PD patients accelerated atherosclerosis processes are actively present. Due to the absence of randomized controlled trials, evidence on the ideal therapeutic strategy for ESKD population with CAD is lacking. Indeed, current practice is mainly based on observational data that are subject to potential bias. Current guidelines are either lacking for HD patients or are derived from trials performed in non-HD patients. Specifically, the risks and benefits of antiplatelet agents in ESKD patients with CAD remain poorly defined; the optimal revascularization strategy for these patients remains unclear.
The purpose of this special issue is to address the complex and unresolved aspects of diagnosis, prevention, and treatment of CAD in HD patients, with respect to both acute coronary syndromes and chronic ischemic heart disease.
Narrative or systematic reviews of data available in the literature as well as original studies addressing the issues illustrated above are welcome.
Prof. Simonetta Genovesi and Dr. Giuseppe Regolisti
Guest Editors
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
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- Open Access ReviewCoronary Artery Disease in CKD-G5D Patients: An UpdatePan Gao, Xingjian Zou, Xin Sun, Chun ZhangRev. Cardiovasc. Med. 2023, 24(8), 227; https://doi.org/10.31083/j.rcm2408227(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)93Downloads219Views
- Open Access ReviewManagement of Cardiovascular Diseases in Chronic Hemodialysis PatientsZhen Zhang, Yaqiong WangRev. Cardiovasc. Med. 2023, 24(7), 185; https://doi.org/10.31083/j.rcm2407185(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)153Downloads314Views
- Open Access ReviewThe Controversies of Coronary Artery Disease in End-Stage Kidney Disease Patients: A Narrative ReviewDaniel Hirsch, Brandon Lau, Virag Kushwaha, Kenneth YongRev. Cardiovasc. Med. 2023, 24(6), 181; https://doi.org/10.31083/j.rcm2406181(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)69Downloads216Views
- Open Access Original ResearchPrognostic Impact of Percutaneous Coronary Intervention in Chronic Dialysis Patients with Acute Myocardial Infarction: Findings from the Lombardy Health DatabaseNicola Cosentino, Simonetta Genovesi, Alice Bonomi, Filippo Trombara, ... Giancarlo MarenziRev. Cardiovasc. Med. 2023, 24(5), 135; https://doi.org/10.31083/j.rcm2405135(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)48Downloads202Views
- Open Access Original ResearchPreexisting Cardiovascular Disease, Hypertension, and Mortality in Peritoneal DialysisJuan Wu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, ... Junnan WuRev. Cardiovasc. Med. 2023, 24(1), 30; https://doi.org/10.31083/j.rcm2401030(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)64Downloads309Views