Treatment of Acute Aortic Dissection in the Current Era: from Early Diagnosis, Treatment to Rehabilitation Pathways

Dear Colleagues,

Despite advances during the last decade in the early diagnosis, surgical treatment, and perioperative care of patients developing acute aortic dissection (AAD), the disease still carries a high risk of mortality, major morbidity, and chronic disability in the early to long-term follow-up. Several surgical techniques have been implemented in the past decades. Similarly, several genetic domains or familial linkages predisposing to the disease have been highlighted. Different radiological tools and biomarkers have been suggested to improve early diagnosis. Several intensive care protocols have been popularized to reduce the ongoing multi-organ damage developing after onset of aortic dissection, as well as to heal the ischemia-reperfusion multiorgan damage occurring with surgery. Despite that, however, the disease still has an incidence of 12% to 50% in recent experiences.

The Special Issue, “Treatment of acute aortic dissection in the current era: from early diagnosis, treatment to rehabilitation pathways” will collect high-quality original research papers and comprehensive reviews on recent advances in the preoperative, intraoperative, and postoperative care of patients developing this severe disease. Topics of interests include but are not limited to:

• Genetics and epigenetics of AAD
• Early diagnostic tools (radiology, cardiology, biochemistry)
• Preoperative risk factors of mortality and/or major morbidity in surgery for AAD, with a special emphasis on futility
• Surgical outcome of AAD (type A, type B, type non-A non-B)
• Original techniques in surgery for AAD
• Outcome of the frozen elephant trunk technique
• Endovascular treatment of AAD
• Conductance of cardiopulmonary bypass and circulatory arrest during AAD
• Outcome of de-branching techniques/approaches
• Perioperative care of patients operated on for AAD
• Rehabilitation of patients after surgery and/or major morbidity following AAD

Manuscripts submitted to this Special Issue will be subjected to stringent selection criteria to ensure the privileged position of accepted contributions. Those that fail to pass this selection will be considered for publication in RCM as regular contributions.

Prof. Francesco Onorati

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.