IMR Press / RCM / Special Issues / 1623058015483

New Frontiers in Cardiac Surgery: Biomarkers and Treatment

Submission deadline: 01 March 2022
Special Issue Editors
  • Carmela Rita Balistreri, MD, PhD
    Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Palermo, Italy
    Interests: Thoracic aortic aneurysom; Bicuspid aortic valve; Longevity, Atherosclerosis; Aorta; Aneurysm; Biomarkers; Inflammation; Genes
    Special Issues and Topics in IMR Press journals
  • Calogera Pisano, MD
    Department of Surgical Science Cardiac Surgery Unit Tor Vergata University, Viale Oxford, 8,00133 Rome, Italy
    Interests: Cardiac surgery; Biomarkers in cardiac surgery; Minimally invasive surgery; Marfan syndrome
Special Issue Information

Dear Colleagues,


Cardiac surgery has evolved in the approaches and strategies in the last years. Accordingly, remarkable innovations in terms of treatments are proposing and applying. Among these, the minimally invasive surgery, and the catheter -based intervention, such as mitral clip implantation, transcatheter aortic valve implantation, transapical mitral valve repair and replacement, are becoming the very objects of interest of clinicians. In addition of this, several evolving techniques and surgical prosthesis have also enriched the surgical armamentarium. Beside new biomarkers have been discovered thanks to identification of cellular and molecular mechanisms involved in cardiovascular diseases, and suggested as potential diagnostic and prognostic tools to optimize the surgical indications of different cardiac surgery pathologies. Consequently, a close interplay between researchers and clinicians can make a difference in upgrading of surgical studies by providing expertise and higher quality for applying new technologies, improving the management of cardiac pathologies with the help of a solid support from the lab analyses, modern recommendations, and algorithms, as well as for investigating “surgical questions”. A harmonious collaboration between researchers and the team of a cardiac surgery unit with several women as components can be the winning key. The clinicians can identify the medical needs and priorities, the researchers can provide the knowledge of the disease’ s mechanisms, the involved pathways, and benefits in the use of related biomarkers and targets for improving management and achieving personal therapies, and “new ideas”. This can lead to propose and test new solutions for the health and the life quality of patients. A new frontier of this close collaboration is, for example, the application of regenerative medicine for cardiac tissue and structure, including gene and cell therapies.  Finally the application of gender medicine can also help to identify accurate biomarkers according to gender, facilitating a differential cardiac disease management. Accordingly, the impact of gender differences in cardiac pathophysiology has been widely demonstrated. In this issue, all these aspects will be described and discussed, as well as potential limitations and future directions in this incipient field.


Assoc. Prof. Dr. Carmela Rita Balistreri and Prof. Calogera Pisano

Guest Editors

Cardiac Diseases
New Surgical Approches
New Blood and Byoptic Biomarkers of Cardiac Diseases
Anti-ageing Medicine in Cardiac Diseases
Stem Cell Therapy
Gene Therapy
New Multiomics Profiles
Gender Medicine
Manuscript Submission Information

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Published Paper (6 Papers)
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