IMR Press / RCM / Special Issues / 1619658565333

Innovations and Contemporary Advances in Advanced Heart Failure, Durable Mechanical Circulatory Support, and Heart Transplantation

Submission deadline: 30 April 2022
Special Issue Editor
  • Ersilia M. DeFilippis, MD
    Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, 622 West 168th Street, New York, New York 10032.
    Interests: Advanced heart failure; Sex differences in heart failure; Health equity
Special Issue Information

Dear Colleagues,


Among the more than 6 million adults in the United States with heart failure, a subset of them will develop advanced heart failure despite our best efforts. Advanced therapies including durable mechanical circulatory support and heart transplantation may be available options for certain patients.

Over the last decade, there have been significant innovations and advances in the approach to advanced heart failure. Results of the MOMENTUM 3 trial suggest that short-term outcomes with the HeartMate 3 left ventricular assist device (LVAD) are similar to heart transplantation. Temporary mechanical circulatory support has also been increasingly used as a bridge to transplantation. The change in the heart transplant organ allocation system that went into effect in October 2018 has had impact on treatment strategies particularly for certain subgroups of individuals. Additionally, strategies have been introduced to increase the donor pool such as transplantation from Hepatitis-C-positive donors as well as donation after circulatory death (DCD) heart transplantation.  


In light of the recent advances and changing landscape of LVAD technology and heart transplantation, we introduce this series of concise reviews to highlight the innovation of the field and contemporary management of these patients in the current day.

We would like to invite experts in the field to write comprehensive reviews (3000 to 5000 words) covering the following topics:

- Risk Factors and Management of Primary Graft Dysfunction
- Strategies for expanding the donor pool for heart transplantation (i.e. use of DCD and Hepatitis C positive donors)
- Impact of the new heart transplant allocation system
- Considerations for dual-organ transplantation
- Future technologies and directions for durable left ventricular assist devices
- Management of pulmonary hypertension in patients on left ventricular assist device support
- Improving access to heart transplantation for under-represented groups
- Palliative care and approach for patients who are not candidates for advanced therapies  


Dr. Ersilia M. DeFilippis

Guest Editor

Heart transplantation
Durable mechanical circulatory support
Left ventricular assist device
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.

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