Thrombosis: Clinical Diagnosis and Treatment

Dear Colleagues,

Thrombosis, defined as the formation of blood clots within the vasculature leading to complete or partial obstruction to blood flow in the vessel, is one of the leading causes of morbidity and mortality in the developed world. It can be both arterial and venous and encompasses a wide variety of diagnoses including the more common myocardial infarction, cerebrovascular accident, acute limb ischemia, deep vein thrombosis/pulmonary embolism to the rare anti-phospholipid syndrome and heparin-induced thrombocytopenia and thrombosis. The incidence and prevalence of thrombosis depend on whether it is arterial or venous. Both forms of thrombosis are associated with poor prognosis with long-term sequelae contributing significantly to the healthcare burden.

The pathophysiology of arterial and venous thrombosis is different and management requires a thorough understanding of the underlying pathophysiology and the location of the thrombus (arterial or venous). Over the years treatment strategies for the management of thrombosis have changed significantly, especially with the advent of newer drugs. While antiplatelet agents are the first choice of drugs for the management of arterial thrombosis, vitamin K antagonists and direct oral anticoagulants are preferred for venous thrombosis. Also, adjunct therapies such as catheter-directed thrombolysis, thrombectomy, and stenting have shown to be efficacious in certain clinical settings.

The topic of ‘Thrombosis’ will be explored further in this special issue of Reviews in Cardiovascular Medicine. We sincerely invite our esteemed colleagues to submit original articles and reviews on the topic “Thrombosis: Clinical Diagnosis and Treatment” with special emphasis on pathophysiology, diagnosis, and treatment strategies, including novel therapies. We believe this issue will help provide practicing clinicians and clinicians-in-training a detailed synopsis of the management of various disorders associated with thrombosis and also form a suitable framework for further research in this field.

Dr. Raviteja R. Guddeti

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.