IMR Press / RCM / Volume 8 / Issue 1 / pii/1561094439505-1164087909

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
The Relationship Among Risk Factor Clustering, Abdominal Obesity, and Residual Risk for Cardiovascular Events
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1 Pennington Biomedical Research Center, Baton Rouge, LA
Rev. Cardiovasc. Med. 2007, 8(1), 9–16;
Published: 30 March 2007
Statins, angiotensin-converting enzyme inhibitors, and combination therapies have been shown to reduce the cardiovascular event rate in susceptible individuals, albeit with remaining significant residual risk. Some of the sources of residual risk, such as genetics and epigenetic phenomena, are not easily modifiable. Still, the risk imposed by these factors may be lowered by implementation of dietary, behavioral, and pharmacologic interventions. Abdominal obesity has emerged as one element in the cluster of factors linked to increased propensity for cardiovascular disease and type 2 diabetes. It is a potential therapeutic target to reduce residual cardiometabolic risk. Waist circumference has been shown to be a strong correlate of abdominal obesity, and measurement is a useful tool for the assessment of cardiometabolic risk.
Cardiovascular risk
Abdominal obesity
Waist circumference
Type 2 diabetes
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