IMR Press / RCM / Volume 7 / Issue 4 / pii/1561344050462-1990791287

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
A Systematic Overview of Anomalous Coronary Anatomy and an Examination of the Association With Sudden Cardiac Death
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1 Department of Internal Medicine, Mayo Clinic, College of Medicine, Rochester, MN
2020 Division of Cardiology, Mayo Clinic, College of Medicine, Rochester, MN
2021 Division of Cardiac Surgery, The Heart, Lung and Esophageal Surgery Institute at the University of Pittsburgh Medical Center (UPMC) Presbyterian, Pittsburgh, PA
Rev. Cardiovasc. Med. 2006, 7(4), 205–213;
Published: 30 December 2006
Abstract
Coronary artery anomalies are a frequently neglected topic in cardiology. However, they are an important cause of cardiac ischemia and sudden death. Anomalous pulmonary artery and anomalous aortic origins of the coronaries are 2 major types of coronary artery anomalies. This article will examine the occurrence of these anomalies in the absence of associated congenital defects. A review of the literature reveals that the anomaly most commonly associated with sudden death is a left main coronary artery arising from the right aortic sinus of Valsalva with an interarterial course. The increased risk of sudden death with this anomaly has been associated with any of 4 high-risk features: slit-like ostium, acute-angle take-off, intramural aortic segment, and interarterial course.
Keywords
Coronary artery anomalies
Sudden cardiac death
Sinus of Valsalva
Pulmonary artery origin
Aortic origin
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