IMR Press / RCM / Volume 6 / Issue 2 / pii/1561344093123-483478999

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
The Proinflammatory and Hypercoagulable State of Diabetes Mellitus
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1 Department of Medicine, Robert Wood Johnson University Hospital, New Brunswick, NJ
2020 Department of Medicine, University of Missouri School of Medicine, Columbia, MO
2021 Division of Cardiology, Robert Wood Johnson University Hospital, New Brunswick, NJ
Rev. Cardiovasc. Med. 2005, 6(2), 84–97;
Published: 30 June 2005
The diabetic population is at high risk for development of cardiovascular disease (CVD), cerebrovascular disease, and peripheral vascular disease. Approximately 80% of these patients die from a thrombotic cause, with CVD complications being involved in 75% of those. The mechanisms involved in the development of coronary artery disease (CAD) in the diabetic population are multifactorial, including hyperglycemia, hyperlipidemia, hypertension, and insulin resistance, ultimately leading to endothelial dysfunction and accelerated atherogenesis. Thus, diabetes has become a CAD risk equivalent. Early and aggressive intervention in treating risk factors may reduce the risk of developing diabetes and may prevent CVD in patients with established diabetes.
Insulin resistance syndrome
Cardiovascular disease
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