IMR Press / RCM / Volume 5 / Issue S1 / pii/1561344981340-217277221

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
Management of Chronic Heart Failure: What Do Recent Clinical Trials Teach Us?
Show Less
1 Kaufman Center for Heart Failure, Section of Heart Failure and Cardiac Transplant Medicine, The Cleveland Clinic Foundation, Cleveland, OH
Rev. Cardiovasc. Med. 2004, 5(S1), 3–9;
Published: 20 January 2004
Abstract
Though understanding and development of new therapies for heart failure (HF) have increased dramatically in recent years, the condition still takes a huge toll in terms of both morbidity and mortality and it is essential to continue with the quest for more effective HF treatments. Clinical trials provide the most precise scientific data regarding efficacy of HF therapies. Over the past 2 decades, about 100 large-scale clinical trials have significantly impacted treatment practices with respect to HF patients. The latest have shown benefit in the use of certain ß-blockers, aldosterone-receptor blockers, and the implantation of biventricular pacing-cardioverter defibrillator devices, generally in conjunction with an aggressive medical therapy regimen. This information should be integrated into existing guidelines for HF patient treatment as the search for greater efficacy in controlling and reversing this disease state continues.
Keywords
Heart failure
ß-Blockers
ACE inhibitors
Aldosterone-receptor blockers
Cardiac resynchronization therapy
Share
Back to top