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Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.
Open Access
Review
Immunotherapy for Atherosclerosis: An Emerging Paradigm
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1
The Atherosclerosis Research Center, Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA
2020
University of Lund, Malmö, Sweden
Rev. Cardiovasc. Med. 2004, 5(4), 194–203;
Published: 30 December 2004
Abstract
Experimental and clinical studies have implicated the immune system in atherogenesis and its complications. Recent studies have identified a complex dual role for the immune system: some aspects of the system play a proatherogenic role, whereas other aspects are atheroprotective. Suppression of proatherogenic immune responses and activation of antiatherogenic immune responses promise to emerge as novel strategies for the prevention and treatment of atherosclerotic vascular disease.
Keywords
Atherosclerosis
Immunosuppression
Vaccination
Tolerization
Low-density lipoprotein
oxidized
Malondialdehyde-apolipoprotein B-100 peptide antigens
Phospholipid antigens
oxidized
Cholesteryl ester transfer protein