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Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.
Open Access
Review
Combining Natriuretic Peptides
and Necrosis Markers in the
Assessment of Acute Coronary
Syndromes
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1
Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX
2020
The TIMI Study Group and Division of Cardiology, Brigham and Women's Hospital, Boston, MA
Rev. Cardiovasc. Med. 2003, 4(S4), 37–46;
Published: 20 July 2003
Abstract
Management of patients with acute coronary syndromes (ACS) is becoming more complex
as the array of treatment options available to patients and physicians continues
to expand. Cardiac biomarkers play an important role in risk stratification in ACS, and
results of cardiac biomarker tests can be used to help guide choices between alternative
therapies. In addition to biomarkers of myocyte necrosis, markers of neurohormonal
activation, such as B-type natriuretic peptide (BNP), provide important prognostic
information in ACS. In the future, multimarker strategies that incorporate panels of
cardiac biomarkers are likely to be used for risk stratification and for pathophysiologyguided
treatment in patients with ACS.
Keywords
Acute coronary syndromes
B-type natriuretic peptide
Cardiac troponins
C-reactive protein
Creatine kinase
Myoglobin