IMR Press / RCM / Volume 16 / Issue 1 / DOI: 10.3909/ricm0725

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
Heart Failure With Preserved Ejection Fraction: An Insight Into Its Prevalence, Predictors, and Implications of Early Detection
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1 Department of Cardiology, The Northern Hospital, Melbourne, Australia
2 Department of Medicine, University of Melbourne, Melbourne, Australia
3 Department of Cardiology, Austin Health, Melbourne, Australia
4 Department of Cardiology, Western Health, Melbourne, Australia
Rev. Cardiovasc. Med. 2015, 16(1), 20–27;
Published: 30 March 2015
Heart failure with preserved ejection fraction (HFPEF) is common, and at least half of patients presenting with signs and symptoms of heart failure are found to have preserved left ventricular systolic function. They have high mortality and morbidity and exert a substantial impact on health care costs worldwide. A range of conditions has been shown to predispose individuals to development of diastolic dysfunction and HFPEF. Chronic hypertension is the most common cause; it has been suggested that up to 60% of patients with HFPEF are hypertensive. Coronary artery disease, obesity, and diabetes are some of the other common contributory factors. Early detection of asymptomatic patients identified as at risk of developing this syndrome has the potential to reduce the risk of subsequent heart failure; this may be of benefit to focus our attention on prevention and intervention strategies in this population.
Heart failure
Diastolic dysfunction
Heart failure with preserved ejection fraction
Heart failure with normal ejection fraction
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