IMR Press / JOMH / Volume 18 / Issue 8 / DOI: 10.31083/j.jomh1808161
Open Access Original Research
De Novo or Increasing Lower Urinary Tract Symptoms during COVID-19 Infection: Long-term Results
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1 Department of Urology, School of Medicine, Sakarya University, 54100 Sakarya, Turkey
2 Department of Microbiology, School of Medicine, Sakarya University, 54100 Sakarya, Turkey
3 Department of Infectious Diseases, School of Medicine, Sakarya University, 54100 Sakarya, Turkey
*Correspondence: (Yavuz Tarık Atik)
J. Mens. Health 2022, 18(8), 161;
Submitted: 2 January 2022 | Revised: 8 February 2022 | Accepted: 7 March 2022 | Published: 19 July 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: How COVID-19 affects lower urinary tract symptoms (LUTS) in men has not been demonstrated by published research. This study examined the de novo development of LUTS and the change in the severity of pre-existing LUTS in men hospitalized with COVID-19. A follow-up period of 12 months after COVID-19 infection provided data on the long-term effect of COVID-19 vs. LUTS. Methods: Data were collected from 70 male patients diagnosed with COVID-19 via nasopharyngeal swab RT-PCR technology between June 2020 and April 2021. The patient’s age, comorbidities, date of COVID-19 diagnosis, date of LUTS, International Prostate Symptom Score (IPSS), prostate-specific antigen (PSA), creatinine, and D-dimer levels, urinalysis, urine culture and duration of hospital stay were recorded. Statistical analyses were conducted to compare between pre-COVID and post-COVID IPSS and other data. Results: 42 patients were included in this study with a, mean age of patients were 54.76 ± 11.95 years. In 8 patients there was no change in IPSS pre- vs. post-COVID. In the remaining 34 patients (80.9%), the median IPSS increased from a pre-COVID value of 2 to 10 during COVID (p < 0.001). In the subgroup analysis based on age <50 years vs. 50 years, statistically significant increase in IPSS were found in both age groups pre- and post-COVID. Conclusions: In male patients of all ages, COVID-19 results in the de novo occurrence of LUTS and an increase in pre-existing LUTS in approximately 80% of patients. These symptoms were found to persist at a 12-months follow-up.

observational study
urinary tract
Fig. 1.
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