IMR Press / JOMH / Volume 18 / Issue 7 / DOI: 10.31083/j.jomh1807150
Open Access Original Research
Daily Dose of 5 mg Tadalafil Safely Improves Erectile Function and Liver Function Enzymes in Smokers
Show Less
1 Department of Family Medicine, Soonchunhyang University Hospital Seoul, 04401 Seoul, Republic of Korea
*Correspondence: byungwookyoo@hanmail.net (Byung Wook Yoo)
J. Mens. Health 2022, 18(7), 150; https://doi.org/10.31083/j.jomh1807150
Submitted: 16 November 2021 | Revised: 17 February 2022 | Accepted: 7 March 2022 | Published: 7 July 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: Smokers are known to have a higher risk of erectile dysfunction. We examined how daily consumption of low-dose tadalafil affected erectile function and circulation in smokers and assessed the medication safety. Methods: Men aged over 20 years with current smoking status were selected to complete four weeks of treatment with 5 mg tadalafil daily. Erectile function was measured using the International Index of Erectile Function (IIEF), and additional tests included measuring various serum parameters, electrocardiogram, and nail capillary blood flow. Results: The IIEF scores, capillary blood flow, and serum liver function enzyme levels significantly improved. There were no reported adverse side effects. Conclusions: Smokers who were administered 5 mg tadalafil daily for four weeks had improved International Index of Erectile Function scores, dilated capillary vessels, and improved blood liver function enzyme levels; proving not only safety of usage and its effectiveness but also possible features that can indicate usages of the drug in other purposes.

Keywords
erectile dysfunction
liver function
smokers
tadalafil
Share
Back to top