IMR Press / JOMH / Volume 18 / Issue 1 / DOI: 10.31083/jomh.2021.064
Open Access Original Research
Sex-specific in the relationship between hyperuricemia and pulse pressure in non-diabetic Korean adults: the 2017 Korean National Health and Nutrition Examination Survey
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1 Department of Radiological Science, Hanlyo University, 57764 Gwangyangsi, South Korea
2 Department of Emergency Medical Technology, Gwangju Health University, 62287 Gwangsan-gu, South Korea
3 Department of Radiology, Cheomdan Hospital, 62274 Gwangsan-gu, South Korea
4 Department of global Medical Beauty, Konyang University, 32992 Nonsan-si, South Korea
5 Department of Biomedical Laboratory Science, Wonkwang Health Science University, 54538 Iksan-si, South Korea
J. Mens. Health 2022, 18(1), 6; https://doi.org/10.31083/jomh.2021.064
Submitted: 12 March 2021 | Accepted: 23 March 2021 | Published: 17 January 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background and objective: The present study assesses the relationship between hyperuricemia and pulse pressure (PP) in non-diabetic Korean adults. Material and methods: Data from 5122 subjects (2251 men and 2871 women) in the seventh Korean National Health and Nutrition Examination Survey (KNHANES VII-2, 2017) were analyzed. Results: Systolic blood pressure (SBP) and PP were significant factors determining the odds ratios (ORs) for hyperuricemia (uric acid 7.0 mg/dL in men or 6.0 mg/dL in women) in men and the overall population. In women, SBP, diastolic blood pressure (DBP), and PP were not significant factors determining the OR for hyperuricemia. After adjusting for related variables, the OR of hyperuricemia was significantly higher in the high PP group (PP >60.0 mmHg) for men (OR, 1.760; 95% confidence interval [CI], 1.152–2.688) and the overall population (OR, 1.557; 95% CI, 1.132–2.140) compared with the normal PP group, but this trend was not seen in women (OR, 1.060; 95% CI, 0.646–1.740). Conclusions: Hyperuricemia was positively associated with PP in non-diabetic Korean men but not in women.

Keywords
Uric acid
Pulse pressure
Systolic blood pressure
Gender difference
Non-diabetic population
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