IMR Press / JOMH / Volume 17 / Issue 2 / DOI: 10.31083/jomh.2021.005
Open Access Review
The interaction of drugs to treat cardiovascular diseases and testosterone therapy, their effects and characteristics
Show Less
1 Department of Pharmacology, Kahramanmaras Sütçü Imam University, Faculty of Medicine, 55120 Kahramanmaras, Turkey
2 Department of Cardiology, Kahramanmaras Sütçü Imam University, Faculty of Medicine, 55120 Kahramanmaras, Turkey
J. Mens. Health 2021, 17(2), 25–31; https://doi.org/10.31083/jomh.2021.005
Submitted: 22 October 2020 | Accepted: 20 November 2020 | Published: 8 April 2021
Abstract

Testosterone is used in the treatment of primary or acquired hypogonadism, constitutional growth retardation, and delayed puberty in male patients. Today, there is a fact that cardiovascular diseases present a high frequency in males with a marked tendency to increase soon. Therefore, the number of men using drugs to treat cardiovascular diseases is increasing rapidly. Cardiovascular drugs, which are frequently used and/or recently introduced, may cause undesirable effects under the heading of drug-drug interaction with testosterone therapy. The number of male patients exposed to these agents may increase rapidly quite soon. In this paper, we reviewed the potential drug-drug interactions between drugs to treat cardiovascular diseases and testosterone treatment considering the pharmacokinetic parameters and experimental animal studies in the literature.

Keywords
Testosterone
Drug interactions
Drug-induced
Cardiovascular drugs
Share
Back to top