Advances in Traumatic Brain Injury

Dear Colleagues,

Traumatic brain injury (TBI) presents in the form of concussion, hemorrhage, contusion, penetrating injury, and diffuse axonal injury, with all types of injury being seen with any injury mechanism. The Glasgow Coma Scale (GCS) is widely used to grade the severity of TBI, although the correlation between severity and prognosis is not always exact. Neurosurgical intervention is reserved for instances in which a structural anomaly is present in the context of a survivable/salvageable injury.

The effects off TBI, even mild, can be chronic and require intervention from multiple professions. These effects are now known to be due to the multiple disrupted molecular networks and axonal injury. Over the years, extensive research into the molecular and cellular mechanisms of TBI has suggested various pharmacological treatments to ameliorate the long-standing complications of this disease, some of which has been corroborated by human trials. Research in animal models and humans have also revealed various clinical interventions that lead to improved outcomes.

In this issue, we will explore advances in the understanding of TBI as well as its treatment from both a basic and clinical science perspective, taking into account their impact on morbidity and mortality. We will also consider the post-acute care of these patients and their journeys to regain a normal, functional, quality of life. 

Dr. Brandon Lucke-Wold and Dr.  Ogaga Urhie

Guest Editors

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.