- Department of Translational Medicine School of Medical Sciences, UNICAMP, Brazil; Department of Molecular and Human Genetics Baylor College of Medicine, Houston, TX, USAInterests: genomics; transcriptomics; pharmacogenomics; epilepsy; neurogenetics; neuropsychiatric; neurological disorders; ADHD
Neurological disorders include a wide range of impairments of the central nervous system such as epilepsy, Alzheimer’s disease, ataxia, multiple sclerosis, Parkinson’s disease, stroke, migraine, neurological infection, brain tumors, head injuries, and others. They affect one billion people worldwide, regardless of education, age, and sex. It is estimated that 6.8 million people die every year due to a neurological condition. In recent years, high-throughput technologies have helped identify several genetic and molecular factors that play important roles in the etiology and pathophysiology of different neurological disorders, enabling the targeting of treatment in a personalized and precise way. However, these studies also have considerable challenges and limitations. Therefore, the main aim of this Special Issue is to provide a wide overview on the state of the art of molecular and biological pathways that play a crucial role in treatment response, approaches to precision therapy, disease models, implementation, and clinical trial challenges. Original research reports, review manuscripts, brief communications, and perspectives are welcome in all areas pertinent to the topic.
Prof. Estela Maria Bruxel and Danielle do Carmo Ferreira Bruno
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