Howard University College of Medicine, Washington, DC, USAInterests: translational medicine; drug discovery; neural signaling and synaptic transmission in the central nervous system; functional organization of the olfactory and limbic system; cellular and network mechanisms of brain function and dysfunction studied with electrophysiological, optical, anatomical, and pharmacological methodsSpecial Issues and Topics in IMR Press journalsSpecial Issue in Mechanisms of Neurological DisordersSpecial Issue in Cellular and Network Mechanisms of Brain FunctionSpecial Issue in Neural signaling mechanisms in olfactory and limbic systems
Dear Colleagues,
Neurodegenerative diseases present with a variety of symptoms. Among these symptoms can be a change in our ability to smell. Research studies, focused on understanding the onset of neurodegenerative pathology and therapeutic interventions to inhibit its causative factors, have shown a crucial role of the olfactory system. This includes both peripheral as well as central nervous system structures such as the olfactory bulb and higher order olfactory cortical areas. Widely different approaches involving behavioral symptom analysis, histopathological and molecular alterations, genetic and environmental influence, and age-related alterations in cellular pathways, indicate a strong correlation of olfactory dysfunction and neurodegeneration. Declining olfactory acuity and deficits present either as an initial symptom or as a prodromal symptom of progressing neurodegeneration of various conditions. Olfactory dysfunction has been associated with most neurodegenerative, neuropsychiatric and communication disorders. Contributors to this Special Issue are invited to present new data or novel experimental techniques. Manuscripts that review and summarize our current understanding of olfactory function in neurodegeneration are welcome. Manuscripts that describe how olfactory processing serves as a biomarker of neuropsychiatric and neurodegenerative disorders in unidentified novel pathways are of special interest.
This Special Issue aims to provide the reader with a comprehensive overview of the current state-of-the-art of olfaction and olfactory dysfunctions in humans and animal models as they relate to neurodegenerative diseases. The Special Issue will address all aspects of this topic ranging from molecular, cellular, and developmental systems, and cognitive and behavioral topics as well as clinical studies.
Prof. Dr. Thomas Heinbockel
Guest Editor
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.