Psychiatric disorders are devastating, complex diseases involving behavioral, emotional, or cognitive dysfunctions. Epidemiological evidence shows that psychiatric disorders including anxiety disorders, major depressive disorder, schizophrenia, bipolar disorders, alcohol/drug abuse, dementia and autism, account for about 14% of the global burden of disease. A growing body of literature suggests that extreme or prolonged stress exposure adversely affects brain structure and function and exacerbates the development of virtually all psychiatric diseases. Understanding how stress impairs the affective function of brain to cause mental illnesses represents one of the hot topics in neuroscience and psychiatry. Significant research efforts have been made towards understanding the underlying mechanisms in the last decades. For example, numerous studies have shown that chronic or prolonged stress exposure causes structural and functional of several brain regions including prefrontal cortex, hippocampus and amygdala, which contributes essentially to stress adversities on mood and emotion. However, the underlying molecular and synaptic mechanisms remain largely unknown.
This special thematic issue will focus on understanding the neuronal mechanisms of stress-related psychiatric disorders, and developing therapeutic interventions for the treatment of psychiatric disorders, we welcome researchers and academicians all around the world to contribute their articles related to this topic.
Prof. Dr. Wenhua Zhang and Prof. Dr. Ping Hu
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.
- Open Access Original ResearchPrenatal exposure of citalopram elicits depression-like and anxiety-like behaviors and alteration of morphology and protein expression of medial prefrontal cortex in young adult miceAqeela Zahra, Le Du, Meng Jia, Muhammad Umar Butt, ... Jianping WuJ. Integr. Neurosci. 2022, 21(2), 61; https://doi.org/10.31083/j.jin2102061(This article belongs to the Special Issue Stress exposure and psychiatric disorders)84Downloads280Views