IMR Press / JIN / Volume 22 / Issue 1 / DOI: 10.31083/j.jin2201025
Open Access Original Research
Neuropathic Pain and Positive Sensory Symptoms in Brachial Plexus Neuropathy: An Exploratory Study of Outcomes after Surgical Decompression and Proposal of a New Sensory Frequency of Symptoms Scale
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1 Postgraduate Department, School of Higher Education in Medicine, National Polytechnic Institute, 07340 Mexico City, Mexico
2 Functional & Stereotactic Neurosurgery & Radiosurgery Service, General Hospital of México, 06720 Mexico City, Mexico
3 Research Direction, General Hospital of Mexico, 06720 Mexico City, Mexico
4 Faculty of Health Sciences, Anahuac University Mexico, 52786 Mexico City, Mexico
*Correspondence: (José D. Carrillo-Ruiz)
Academic Editor: Parisa Gazerani
J. Integr. Neurosci. 2023, 22(1), 25;
Submitted: 11 July 2022 | Revised: 29 August 2022 | Accepted: 27 September 2022 | Published: 17 January 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: There are no articles that aim to evaluate the specific role of surgical decompression on the recovery of pain and positive sensory symptoms (PSS) in patients with brachial plexus neuropathy (BPN), as well as the relationship between pain and frequency of sensory manifestations. Methods: A prospective before and after study was performed, considering the pain intensity through the visual analogue scale (VAS), and the frequency of PSS through a proposed new scale: Sensory Frequency of Symptoms Scale (SFSS). To compare the patients before and after the intervention, a paired T-test, a Wilcoxon signed-rank test, and Cohen’s D test were made, coupled with a Spearman analysis in order to establish the relationship between pain and PSS. Results: Sixteen patients were included in the study, the clinical evaluation showed changes in pain according with VAS, going from a mean preoperative state of 8.19 to 1.31 after surgery, showing significant changes (84%, p < 0.00006, Δ = 2.776). Within the PSS, a significant decrease was observed in paresthesias (74%, p < 0.0001, Δ = 1.645), dysesthesias (80%, p < 0.002, Δ = 1.453), and allodynia (70%, p = 0.031, Δ = 0.635). Conversely, the preoperative correlation analysis between pain and dysesthesias/allodynia showed a low and non-significant relationship (R < 0.4, p > 0.05). Conclusions: Surgical decompression is an effective technique for the relief of pain and sensory manifestations in adult patients with BPN of compressive origin. No relationship was observed between pain and dysesthesias/allodynia. Therefore, during clinical evaluation, they should be considered as independent manifestations, highlighting the need to validate new scales.

brachial plexus neuropathy
Fig. 1.
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