IMR Press / FBS / Volume 15 / Issue 1 / DOI: 10.31083/j.fbs1501002
Open Access Case Report
Abscopal Effect Following Cryoablation in a Patient with Metastatic Breast Cancer
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1 Department of Surgery, Mayo Clinic, Jacksonville, FL 32224, USA
2 Department of Oncology, Mayo Clinic, Jacksonville, FL 32224, USA
*Correspondence: (Emmanuel Gabriel)
Academic Editor: Gustavo Caetano-Anollés
Front. Biosci. (Schol Ed) 2023, 15(1), 2;
Submitted: 3 June 2022 | Revised: 24 August 2022 | Accepted: 2 December 2022 | Published: 16 January 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

While breast cancer is a common disease with many available treatment options, many patients still have limited responses, especially those with metastatic breast cancer. Surgery of the primary tumor or metastatic sites is often not part of the treatment regimen for patients with metastatic breast cancer. Cryoablation is a relatively non-invasive procedure that is being investigated for patients with breast cancer. Patients with metastatic breast cancer who are not surgical candidates may derive benefit from cryoablation through the abscopal effect. In this case report, we present a patient with stage IV breast cancer who was treated with cryoablation of the primary breast tumor and showed evidence of an abscopal effect in regional and distant metastases.

metastatic breast cancer
abscopal effect
Fig. 1.
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