IMR Press / FBS / Volume 14 / Issue 1 / DOI: 10.31083/j.fbs1401007
Open Access Review
Role of Cardiac Magnetic Resonance in the Diagnosis of Infiltrative, Hypertrophic, and Arrhythmogenic Cardiomyopathies
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1 Medical Imaging Department, Coimbra Hospital and University Center, 3000-075 Coimbra, Portugal
2 Cardiology Department, Coimbra Hospital and University Center, 3000-075 Coimbra, Portugal
3 Institute of Experimental Pathology, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
4 Institute for Clinical and Biomedical Research (iCBR), Area of Environment, Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
5 Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3000-548 Coimbra, Portugal
6 Clinical Academic Center of Coimbra (CACC), 3000-075 Coimbra, Portugal
7 Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
8 Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
*Correspondence: pedroalmeida.pmca@gmail.com (Pedro Carvalho Almeida)
These authors contributed equally.
Academic Editor: Gustavo Caetano-Anollés
Front. Biosci. (Schol Ed) 2022, 14(1), 007; https://doi.org/10.31083/j.fbs1401007
Submitted: 24 December 2021 | Revised: 12 February 2022 | Accepted: 22 February 2022 | Published: 8 March 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Cardiac magnetic resonance has become a reliable imaging modality providing structural and functional data, and fundamental information about tissue composition. Cardiac magnetic resonance imaging with late gadolinium enhancement, T1-mapping, T2-mapping, T2*-imaging, and extracellular volume, has proved to be a valuable tool in investigating the etiology of heart failure. Such analysis is helpful for the diagnostic evaluation of both ischemic and non-ischemic cardiomyopathies. As primary heart muscle diseases, the ability to characterize the myocardial substrate is essential. Determining the heart failure etiology is fundamental and has implications regarding the prognosis prediction and best treatment. Investigation in cardiac magnetic resonance in heart failure patients has grown in the past decade, and the true value of this imaging modality to detect early disease likely remains underestimated. This review describes the importance of cardiac magnetic resonance for the diagnosis and prognosis of non-ischemic cardiomyopathies, particularly hypertrophic, infiltrative, and arrhythmogenic cardiomyopathies.

Keywords
cardiac magnetic resonance
heart failure
cardiomyopathies
myocardium
late gadolinium enhancement
T1 mapping
hypertrophic cardiomyopathy
amyloidosis
arrhythmogenic cardiomyopathy
Figures
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