IMR Press / FBL / Special Issues / mitochondrial_dysfunction

Mitochondrial Dysfunction in Acute and Chronic Neurodegeneration

Submission deadline: 31 December 2022
Special Issue Editors
  • Giacomo Lazzarino, PhD
    UniCamillus - Saint Camillus International University of Health and Medical Sciences, Rome, Italy
    Interests: Mitochondrial dysfunction; Energy Metabolism; Acute and Chronic Neurodegenerations; Traumatic Brain Injury; Multiple Sclerosis; Amyotrophic Lateral Sclerosis; Cancer Metabolism
  • Nunzio Vicario, PhD
    Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
    Interests: Neuroinflammation; Neurodegeneration; Intercellular communication; Neuroglia; Stem cell
Special Issue Information

Dear Colleagues,

A Pubmed search for “Mitochondrial dysfunction + neurodegeneration” conducted on January 14, 2022, revealed that 1,809 full-length papers had been published up to this date. This highlights the central role of mitochondria in the pathobiological mechanisms of development and progression of acute (stroke, traumatic brain injury) and chronic (amyotrophic lateral sclerosis, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, etc.) neurodegeneration. A better understanding of the biochemical/metabolic/molecular processes involving mitochondrial malfunction in acute and chronic neurodegeneration may allow the development of new and more effective pharmacological treatments. 

The goal of this special issue is to present new advances that connect alterations in mitochondrial function with the onset and/or progression of acute and chronic neurodegeneration. These new findings can be obtained from either experimental cellular/animal models or from clinical studies. Papers reporting the results of new drug treatments that target mitochondria are most welcome. Reviews highlighting the most recent information on specific acute or chronic neurodegenerative diseases will also be considered.

Dr. Giacomo Lazzarino and Dr. Nunzio Vicario

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

Published Paper (1 Paper)
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