IMR Press / FBL / Special Issues / fgf_signaling

Fibroblast Growth Factor (FGF) Signaling

Submission deadline: 30 November 2022
Special Issue Editors
  • Fen Wang, PhD
    Institute of Biosciences and Technology, Texas A&M University, Houston, TX, USA
    Interests: molecular basis of cell signaling; and how aberrant cell signaling leads to birth defects and causes cancers
  • Yuepeng Ke, PhD
    Institute of Biosciences and Technology, Texas A&M University, Houston, TX, USA
    Interests: role of fibroblast growth factor receptor (FGFR) signaling in prostate cancer progression; how FGFR facilitates cancer metabolic reprogramming and immune evasion
Special Issue Information

Dear Colleagues,

Fibroblast growth factors (FGFs) are broadly expressed, and play a vital role in wide-ranging biological activities. Most FGFs signal through FGF receptors (FGFRs), which are encoded by four highly homologous genes, and complex with heparan sulfate polysaccharides or klothos co-factors. Thus, FGFs activate both canonical, and non-canonical, downstream signaling cascades. Both intrinsic and ectopic FGF signaling has been reported to underlie multiple diseases including cancer, cardiovascular disease, autoimmune disease, embryonic development disorder, metabolism, and neurological disorders. Understanding the pathogenic role of FGF signaling can help provide new insights into therapeutic approaches.

The aim of this Special Issue is to highlight scientific breakthroughs related, but not limited, to FGF signaling in cancer, development, and metabolism. This Special Issue will cover a selection of manuscripts that focus on FGF/FGFR and their signaling cascades. 

Prof. Fen Wang and Dr. Yuepeng Ke

Guest Editors

signaling cascade
transmembrane tyrosine kinase
therapeutic approaches
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

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