IMR Press / FBL / Special Issues / autoimmunity

New Frontiers in Mesenchymal Stem Cell Immunomodulation and Regenerative Medicine

Submission deadline: 31 August 2022
Special Issue Editors
  • Nicoletta Eliopoulos, PhD
    Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada
    Interests: MSCs for regenerative medicine; cell therapy; gene therapy
  • Shant Der Sarkissian, PhD
    Département de Chirurgie, Université de Montréal, Montreal, Quebec, Canada
    Interests: MSCs for regenerative medicine
  • Moutih Rafei, PhD
    Département de Pharmacologie et Physiologie, Université de Montréal, Montréal, Quebec, Canada
    Interests: Cancer Immunotherapy; Vaccines; Cell Therapy; Cytokine Engineering
Special Issue Information

Dear Colleagues,

Mesenchymal stroma cells (MSCs) have a spindle- or fibroblast-like shape. Although originally isolated from the bone marrow, several studies revealed that MSCs are also present in a variety of other tissues. In addition, they possess multipotent differentiation capacity in vitro that can give rise to bone, cartilage, tendon, ligament, adipocytes, dermis, muscle and connective tissue, hence their extensive use in the field of regenerative medicine. The accumulated knowledge on MSC biology suggests these cells do not represent a homogenous population. This may explain observed differences in their mode of action, marker expression and secretion profile. MSCs have regenerative and immunomodulatory capacity via the secretion of bioactive factors including small molecules, exosomes and microvesicles. T heir involvement in efferocytosis by phagocytes such as monocytes or macrophages, as well as other regulatory effects means that MSCs are very valuable for cell-based therapies. This special issue will focus on novel properties and concepts relating to the biology of MSCs, as well as their potential utility as therapeutic cells for the treatment of major human illnesses such as auto-immune diseases or for the repair of damaged cells and tissues.

Assoc. Prof. Shant Der Sarkissian, Assoc. Prof. Moutih Rafei and Assis. Prof. Nicoletta Eliopoulos

Guest Editors

Keywords
Mesenchymal Stromal Cells
Efferocytosis
Immune-suppression
Regenerative Therapy
Autoimmunity
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

Back to top