- Raffaele CapassoDepartment of Agricultural Sciences, University of Naples Federico II, Portici, ItalyInterests: Pharmacology; Natural products; Neurotransmission; Behavioral pharmacology; Experimental pharmacology; Preclinical pharmacology; CB1 receptor; PPARs; Cannabinoids; Endocannabinoids; CB2 receptor; TRP
In recent years, among the different classes of receptors linked to the activity of cannabinoids and congeners, great attention has focused on the role of receptors activated by the peroxisome proliferator-activated receptor (PPAR) family. This family includes PPARα, PPARβ/δ, and PPARγ. PPARα activity is mainly involved in the metabolism of lipids, carbohydrates and amino acids, whereas PPARγ is principally serves in the regulation of adipogenesis, energy balance, and lipid biosynthesis. The PPARβ/δ family member regulates the oxidation of fatty acids in skeletal and cardiac muscles. Several studies show that both natural and synthetic ligands, such as fatty acids, phytanic acid, fibrates, and palmitoylethanolamide, can regulate the expression and function of PPARs and that this can be leveraged for the treatment of various human ailments. This special issue will focus on our current understanding of the molecular mechanisms and roles of PPARs in nutrition and health, as well as their value as therapeutic targets for treatment of disease.
Prof. Raffaele Capasso
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.
- Fenofibrate Attenuates Radiation-Induced Oxidative Damage to the Skin through Fatty Acid Binding Protein 4 (FABP4)Chuntang Sun, Bin Song, Wenjiong Sheng, Daojiang Yu, ... Shuyu ZhangFront. Biosci. (Landmark Ed) 2022, 27(7), 214; https://doi.org/10.31083/j.fbl2707214(This article belongs to the Special Issue The Role of PPAR Receptors in Human Health)53Download229Views