IMR Press / FBL / Special Issues / 1470582356833607681

The Role of PPAR Receptors in Human Health

Submission deadline: 01 December 2022
Special Issue Editor
  • Raffaele Capasso
    Department of Agricultural Sciences, University of Naples Federico II, Portici, Italy
    Interests: Pharmacology; Natural products; Neurotransmission; Behavioral pharmacology; Experimental pharmacology; Preclinical pharmacology; CB1 receptor; PPARs; Cannabinoids; Endocannabinoids; CB2 receptor; TRP
Special Issue Information

Dear Colleagues,

In recent years, among the different classes of receptors linked to the activity of cannabinoids and congeners, great attention has focused on the role of receptors activated by the peroxisome proliferator-activated receptor (PPAR) family. This family includes PPARα, PPARβ/δ, and PPARγ. PPARα activity is mainly involved in the metabolism of lipids, carbohydrates and amino acids, whereas PPARγ is principally serves in the regulation of adipogenesis, energy balance, and lipid biosynthesis. The PPARβ/δ family member regulates the oxidation of fatty acids in skeletal and cardiac muscles. Several studies show that both natural and synthetic ligands, such as fatty acids, phytanic acid, fibrates, and palmitoylethanolamide, can regulate the expression and function of PPARs and that this can be leveraged for the treatment of various human ailments. This special issue will focus on our current understanding of the molecular mechanisms and roles of PPARs in nutrition and health, as well as their value as therapeutic targets for treatment of disease.

Prof. Raffaele Capasso

Guest Editor

Keywords
PPAR receptors
Natural and synthetic molecules
Intracellular cascades
PPARs and nutrition
PPARs and health
Manuscript Submission Information

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Published Paper (1 Paper)
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