In recent years, among the different classes of receptors linked to the activity of cannabinoids and congeners, great attention has focused on the role of receptors activated by the peroxisome proliferator-activated receptor (PPAR) family. This family includes PPARα, PPARβ/δ, and PPARγ. PPARα activity is mainly involved in the metabolism of lipids, carbohydrates and amino acids, whereas PPARγ is principally serves in the regulation of adipogenesis, energy balance, and lipid biosynthesis. The PPARβ/δ family member regulates the oxidation of fatty acids in skeletal and cardiac muscles. Several studies show that both natural and synthetic ligands, such as fatty acids, phytanic acid, fibrates, and palmitoylethanolamide, can regulate the expression and function of PPARs and that this can be leveraged for the treatment of various human ailments. This special issue will focus on our current understanding of the molecular mechanisms and roles of PPARs in nutrition and health, as well as their value as therapeutic targets for treatment of disease.
Prof. Raffaele Capasso
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
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